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TEC
2008
99views more  TEC 2008»
13 years 7 months ago
A Drug Candidate Design Environment Using Evolutionary Computation
Abstract-- This article describes the Candidate Design Environment we developed for efficient identification of promising drug candidates. Developing effective drugs from active mo...
M. Ihsan Ecemis, J. Wikel, C. Bingham, Eric Bonabe...
ESWA
2008
195views more  ESWA 2008»
13 years 7 months ago
Automatic expert identification using a text categorization technique in knowledge management systems
Since tacit knowledge such as know-how and experiences is hard to be managed effectively using information technology, it is recently proposed that providing an appropriate expert...
Kun-Woo Yang, Soon-Young Huh
RSCTC
1998
Springer
175views Fuzzy Logic» more  RSCTC 1998»
13 years 11 months ago
Business Process Understanding: Mining Many Datasets
Abstract. Institutional databases can be instrumental in understanding a business process, but additional data may broaden the empirical perspective on the investigated process. We...
Jan M. Zytkow, Arun P. Sanjeev
NAR
2006
108views more  NAR 2006»
13 years 7 months ago
GLIDA: GPCR-ligand database for chemical genomic drug discovery
G-protein coupled receptors (GPCRs) represent one of the most important families of drug targets in pharmaceutical development. GPCR-LIgand DAtabase (GLIDA) is a novel public GPCR...
Yasushi Okuno, Jiyoon Yang, Kei Taneishi, Hiroaki ...
IDA
2003
Springer
14 years 22 days ago
Large Scale Mining of Molecular Fragments with Wildcards
The main task of drug discovery is to find novel bioactive molecules, i.e., chemical compounds that, for example, protect human cells against a virus. One way to support solving t...
Heiko Hofer, Christian Borgelt, Michael R. Berthol...