The HATS project develops a formal method for the design, analysis, and implementation of highly adaptable software systems that are at the same time characterized by a high demand...
With the success of model-driven development as well as component-based and service-oriented systems, models of software architecture are key artefacts in the development process. ...
A powerful new software concept to physiologically based pharmacokinetic (PBPK) modelling of drug disposition is presented. It links the inherent modular understanding in pharmacol...
As an object-oriented system evolves, its architecture tends to drift away from the original design. Knowledge of how the system has changed at coarse-grained levels is key to und...
Predicting stability in object-oriented (OO) software, i.e., the ease with which a software item evolves while preserving its design, is a key feature for software maintenance. In...