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» Structural Protein Interactions: From Months to Minutes
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BMCBI
2004
93views more  BMCBI 2004»
13 years 8 months ago
Predicting binding sites of hydrolase-inhibitor complexes by combining several methods
Background: Protein-protein interactions play a critical role in protein function. Completion of many genomes is being followed rapidly by major efforts to identify interacting pr...
Taner Z. Sen, Andrzej Kloczkowski, Robert L. Jerni...
BMCBI
2005
61views more  BMCBI 2005»
13 years 8 months ago
Proteins with two SUMO-like domains in chromatin-associated complexes: The RENi (Rad60-Esc2-NIP45) family
Background: Post-translational modification by Small Ubiquitin-like Modifiers (SUMO) has been implicated in protein targeting, in the maintenance of genomic integrity and in trans...
Maria Novatchkova, Andreas Bachmair, Birgit Eisenh...
NAR
2006
74views more  NAR 2006»
13 years 8 months ago
NOPdb: Nucleolar Proteome Database
The Nucleolar Proteome Database (NOPdb) archives data on .700 proteins that were identified by multiple mass spectrometry (MS) analyses from highly purified preparations of human ...
Anthony Kar Lun Leung, Laura Trinkle-Mulcahy, Yun ...
BMCBI
2005
115views more  BMCBI 2005»
13 years 8 months ago
SUPERFICIAL - Surface mapping of proteins via structure-based peptide library design
Background: The determination of protein surfaces and the detection of binding sites are essential to our understanding of protein-protein interactions. Such binding sites can be ...
Andrean Goede, Ines S. Jaeger, Robert Preissner
BMCBI
2008
106views more  BMCBI 2008»
13 years 8 months ago
Identification of hot-spot residues in protein-protein interactions by computational docking
Background: The study of protein-protein interactions is becoming increasingly important for biotechnological and therapeutic reasons. We can define two major areas therein: the s...
Solène Grosdidier, Juan Fernández-Re...