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BMCBI
2008
242views more  BMCBI 2008»
13 years 10 months ago
New time-scale criteria for model simplification of bio-reaction systems
Background: Quasi-steady state approximation (QSSA) based on time-scale analysis is known to be an effective method for simplifying metabolic reaction system, but the conventional...
Junwon Choi, Kyung-won Yang, Tai-yong Lee, Sang Yu...
BMCBI
2008
118views more  BMCBI 2008»
13 years 10 months ago
Virtual screening of GPCRs: An in silico chemogenomics approach
The G-protein coupled receptor (GPCR) superfamily is currently the largest class of therapeutic targets. In silico prediction of interactions between GPCRs and small molecules is ...
Laurent Jacob, Brice Hoffmann, Véronique St...
BMCBI
2008
149views more  BMCBI 2008»
13 years 10 months ago
All-paths graph kernel for protein-protein interaction extraction with evaluation of cross-corpus learning
Background: Automated extraction of protein-protein interactions (PPI) is an important and widely studied task in biomedical text mining. We propose a graph kernel based approach ...
Antti Airola, Sampo Pyysalo, Jari Björne, Tap...
COMPUTER
2008
86views more  COMPUTER 2008»
13 years 10 months ago
Supporting Acquisition of Basic Skills
ors induce aptitudes: abstract skills and knowledge. Mentors foster attitudes: social skills and graces. In my experience of school, starting 70 years or so ago, quite regimented i...
W. Neville Holmes
BMCBI
2006
116views more  BMCBI 2006»
13 years 10 months ago
Optimized mixed Markov models for motif identification
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
Weichun Huang, David M. Umbach, Uwe Ohler, Leping ...
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