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BC
2002
193views more  BC 2002»
13 years 7 months ago
Resonant spatiotemporal learning in large random recurrent networks
Taking a global analogy with the structure of perceptual biological systems, we present a system composed of two layers of real-valued sigmoidal neurons. The primary layer receives...
Emmanuel Daucé, Mathias Quoy, Bernard Doyon
BMCBI
2004
83views more  BMCBI 2004»
13 years 7 months ago
VKCDB: Voltage-gated potassium channel database
Background: The family of voltage-gated potassium channels comprises a functionally diverse group of membrane proteins. They help maintain and regulate the potassium ion-based com...
Bin Li, Warren J. Gallin
BMCBI
2004
196views more  BMCBI 2004»
13 years 7 months ago
MUSCLE: a multiple sequence alignment method with reduced time and space complexity
Background: In a previous paper, we introduced MUSCLE, a new program for creating multiple alignments of protein sequences, giving a brief summary of the algorithm and showing MUS...
Robert C. Edgar
BMCBI
2004
96views more  BMCBI 2004»
13 years 7 months ago
A hybrid clustering approach to recognition of protein families in 114 microbial genomes
Background: Grouping proteins into sequence-based clusters is a fundamental step in many bioinformatic analyses (e.g., homology-based prediction of structure or function). Standar...
Timothy J. Harlow, J. Peter Gogarten, Mark A. Raga...
BMCBI
2004
112views more  BMCBI 2004»
13 years 7 months ago
SPOC: A widely distributed domain associated with cancer, apoptosis and transcription
Background: The Split ends (Spen) family are large proteins characterised by N-terminal RNA recognition motifs (RRMs) and a conserved SPOC (Spen paralog and ortholog C-terminal) d...
Luis Sánchez-Pulido, Ana María Rojas...