Abstract. Emerging research demonstrates the potential of proteinprotein interaction (PPI) networks in uncovering the mechanistic bases of cancers, through identification of intera...
Salim A. Chowdhury, Rod K. Nibbe, Mark R. Chance, ...
Abstract. Recent genome sequencing studies have shown that the somatic mutations that drive cancer development are distributed across a large number of genes. This mutational heter...
Background: Colon cancer is driven by mutations in a number of genes, the most notorious of which is Apc. Though much of Apc's signaling has been mechanistically identified o...