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» Subtle Motif Discovery for Detection of DNA Regulatory Sites
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BMCBI
2008
172views more  BMCBI 2008»
13 years 7 months ago
Compo: composite motif discovery using discrete models
Background: Computational discovery of motifs in biomolecular sequences is an established field, with applications both in the discovery of functional sites in proteins and regula...
Geir Kjetil Sandve, Osman Abul, Finn Drablø...
PSB
2004
13 years 8 months ago
Motif Discovery in Heterogeneous Sequence Data
This paper introduces the first integrated algorithm designed to discover novel motifs in heterogeneous sequence data, which is comprised of coregulated genes from a single genome...
Amol Prakash, Mathieu Blanchette, Saurabh Sinha, M...
PSB
2004
13 years 8 months ago
Phylogenetic Motif Detection by Expectation-Maximization on Evolutionary Mixtures
ct The preferential conservation of transcription factor binding sites implies that non-coding sequence data from related species will prove a powerful asset to motif discovery. We...
Alan M. Moses, Derek Y. Chiang, Michael B. Eisen
IMSCCS
2006
IEEE
14 years 1 months ago
Combining Comparative Genomics with de novo Motif Discovery to Identify Human Transcription Factor DNA-Binding Motifs
Background: As more and more genomes are sequenced, comparative genomics approaches provide a methodology for identifying conserved regulatory elements that may be involved in gen...
Linyong Mao, W. Jim Zheng
CSB
2005
IEEE
125views Bioinformatics» more  CSB 2005»
14 years 1 months ago
Discriminative Discovery of Transcription Factor Binding Sites from Location Data
Motivation: The availability of genome-wide location analyses based on chromatin immunoprecipitation (ChIP) data gives a new insight for in silico analysis of transcriptional regu...
Yuji Kawada, Yasubumi Sakakibara