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BMCBI
2006
171views more  BMCBI 2006»
13 years 7 months ago
The effect of oligonucleotide microarray data pre-processing on the analysis of patient-cohort studies
Background: Intensity values measured by Affymetrix microarrays have to be both normalized, to be able to compare different microarrays by removing non-biological variation, and s...
Roel G. W. Verhaak, Frank J. T. Staal, Peter J. M....
BMCBI
2004
180views more  BMCBI 2004»
13 years 7 months ago
Noise filtering and nonparametric analysis of microarray data underscores discriminating markers of oral, prostate, lung, ovaria
Background: A major goal of cancer research is to identify discrete biomarkers that specifically characterize a given malignancy. These markers are useful in diagnosis, may identi...
Virginie M. Aris, Michael J. Cody, Jeff Cheng, Jam...
BMCBI
2008
99views more  BMCBI 2008»
13 years 7 months ago
Ranking analysis of F-statistics for microarray data
Background: Microarray technology provides an efficient means for globally exploring physiological processes governed by the coordinated expression of multiple genes. However, ide...
Yuan-De Tan, Myriam Fornage, Hongyan Xu
BMCBI
2006
200views more  BMCBI 2006»
13 years 7 months ago
Comparison and evaluation of methods for generating differentially expressed gene lists from microarray data
Background: Numerous feature selection methods have been applied to the identification of differentially expressed genes in microarray data. These include simple fold change, clas...
Ian B. Jeffery, Desmond G. Higgins, Aedín C...
BMCBI
2006
181views more  BMCBI 2006»
13 years 7 months ago
Array2BIO: from microarray expression data to functional annotation of co-regulated genes
Background: There are several isolated tools for partial analysis of microarray expression data. To provide an integrative, easy-to-use and automated toolkit for the analysis of A...
Gabriela G. Loots, Patrick S. G. Chain, Shalini Ma...