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» Support Vector Machines for Predicting microRNA Hairpins
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BMCBI
2011
12 years 11 months ago
Elastic SCAD as a novel penalization method for SVM classification tasks in high-dimensional data
Background: Classification and variable selection play an important role in knowledge discovery in highdimensional data. Although Support Vector Machine (SVM) algorithms are among...
Natalia Becker, Grischa Toedt, Peter Lichter, Axel...
ICMLA
2010
13 years 5 months ago
Smoothing Gene Expression Using Biological Networks
Gene expression (microarray) data have been used widely in bioinformatics. The expression data of a large number of genes from small numbers of subjects are used to identify inform...
Yue Fan, Mark A. Kon, Shinuk Kim, Charles DeLisi
EVOW
2006
Springer
13 years 11 months ago
Functional Classification of G-Protein Coupled Receptors, Based on Their Specific Ligand Coupling Patterns
Functional identification of G-Protein Coupled Receptors (GPCRs) is one of the current focus areas of pharmaceutical research. Although thousands of GPCR sequences are known, many ...
Burcu Bakir, Osman Ugur Sezerman
JMLR
2011
148views more  JMLR 2011»
13 years 2 months ago
Multitask Sparsity via Maximum Entropy Discrimination
A multitask learning framework is developed for discriminative classification and regression where multiple large-margin linear classifiers are estimated for different predictio...
Tony Jebara
BMCBI
2008
124views more  BMCBI 2008»
13 years 7 months ago
Computational identification of ubiquitylation sites from protein sequences
Background: Ubiquitylation plays an important role in regulating protein functions. Recently, experimental methods were developed toward effective identification of ubiquitylation...
Chun-Wei Tung, Shinn-Ying Ho