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BMCBI
2008
140views more  BMCBI 2008»
13 years 7 months ago
SCPRED: Accurate prediction of protein structural class for sequences of twilight-zone similarity with predicting sequences
Background: Protein structure prediction methods provide accurate results when a homologous protein is predicted, while poorer predictions are obtained in the absence of homologou...
Lukasz A. Kurgan, Krzysztof J. Cios, Ke Chen 0003
BMCBI
2010
182views more  BMCBI 2010»
13 years 7 months ago
L2-norm multiple kernel learning and its application to biomedical data fusion
Background: This paper introduces the notion of optimizing different norms in the dual problem of support vector machines with multiple kernels. The selection of norms yields diff...
Shi Yu, Tillmann Falck, Anneleen Daemen, Lé...
WABI
2009
Springer
155views Bioinformatics» more  WABI 2009»
14 years 1 months ago
A Markov Classification Model for Metabolic Pathways
Background: This paper considers the problem of identifying pathways through metabolic networks that relate to a specific biological response. Our proposed model, HME3M, first ide...
Timothy Hancock, Hiroshi Mamitsuka
SDM
2010
SIAM
146views Data Mining» more  SDM 2010»
13 years 8 months ago
Towards Finding Valuable Topics
Enterprises depend on their information workers finding valuable information to be productive. However, existing enterprise search and recommendation systems can exploit few studi...
Zhen Wen, Ching-Yung Lin
UAI
2003
13 years 8 months ago
On the Convergence of Bound Optimization Algorithms
Many practitioners who use EM and related algorithms complain that they are sometimes slow. When does this happen, and what can be done about it? In this paper, we study the gener...
Ruslan Salakhutdinov, Sam T. Roweis, Zoubin Ghahra...