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BMCBI
2008
13 years 8 months ago
2008
Background: Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) ...
BMCBI
2008
13 years 8 months ago
2008
Background: Probability based statistical learning methods such as mutual information and Bayesian networks have emerged as a major category of tools for reverse engineering mecha...
BMCBI
2008
13 years 8 months ago
2008
Background: Target identification is important for modern drug discovery. With the advances in the development of molecular docking, potential binding proteins may be discovered b...
BMCBI
2008
13 years 8 months ago
2008
Background: Confidence in pairwise alignments of biological sequences, obtained by various methods such as Blast or Smith-Waterman, is critical for automatic analyses of genomic d...
BMCBI
2008
13 years 8 months ago
2008
Background: The engineering of ontologies, especially with a view to a text-mining use, is still a new research field. There does not yet exist a well-defined theory and technolog...