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BMCBI
2010
99views more  BMCBI 2010»
13 years 9 months ago
Different effects of the probe summarization algorithms PLIER and RMA on high-level analysis of Affymetrix exon arrays
Background: Alternative splicing is an important mechanism that increases protein diversity and functionality in higher eukaryotes. Affymetrix exon arrays are a commercialized pla...
Yi Qu, Fei He, Yuchen Chen
BMCBI
2010
104views more  BMCBI 2010»
13 years 9 months ago
Response network analysis of differential gene expression in human epithelial lung cells during avian influenza infections
Background: The recent emergence of the H5N1 influenza virus from avian reservoirs has raised concern about future influenza strains of high virulence emerging that could easily i...
Ken Tatebe, Ahmet Zeytun, Ruy M. Ribeiro, Robert H...
BMCBI
2008
138views more  BMCBI 2008»
13 years 9 months ago
Application of nonnegative matrix factorization to improve profile-profile alignment features for fold recognition and remote ho
Background: Nonnegative matrix factorization (NMF) is a feature extraction method that has the property of intuitive part-based representation of the original features. This uniqu...
Inkyung Jung, Jaehyung Lee, Soo-Young Lee, Dongsup...
CONSTRAINTS
2010
126views more  CONSTRAINTS 2010»
13 years 9 months ago
Lexicographically-ordered constraint satisfaction problems
Abstract. We describe a simple CSP formalism for handling multi-attribute preference problems with hard constraints, one that combines hard constraints and preferences so the two a...
Eugene C. Freuder, Robert Heffernan, Richard J. Wa...
CORR
2010
Springer
249views Education» more  CORR 2010»
13 years 9 months ago
Lower Bounds on Near Neighbor Search via Metric Expansion
In this paper we show how the complexity of performing nearest neighbor (NNS) search on a metric space is related to the expansion of the metric space. Given a metric space we loo...
Rina Panigrahy, Kunal Talwar, Udi Wieder