Background: Feature gene extraction is a fundamental issue in microarray-based biomarker discovery. It is normally treated as an optimization problem of finding the best predictiv...
Chi Kin Chow, Hai Long Zhu, Jessica Lacy, Winston ...
Linear Discriminant Analysis (LDA) is one of the wellknown methods for supervised dimensionality reduction. Over the years, many LDA-based algorithms have been developed to cope w...
Order-preserving submatrixes (OPSMs) have been accepted as a biologically meaningful subspace cluster model, capturing the general tendency of gene expressions across a subset of ...
Byron J. Gao, Obi L. Griffith, Martin Ester, Steve...
Abstract--High-dimensional data are common in many domains, and dimensionality reduction is the key to cope with the curse-of-dimensionality. Linear discriminant analysis (LDA) is ...
Background: The extended use of microarray technologies has enabled the generation and accumulation of gene expression datasets that contain expression levels of thousands of gene...
Pedro Carmona-Saez, Roberto D. Pascual-Marqui, Fra...