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» Synthesizing Stochasticity in Biochemical Systems
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ICASSP
2011
IEEE
12 years 11 months ago
Message-passing for base-calling in sequencing-by-synthesis systems
Performance of DNA sequencing-by-synthesis systems is fundamentally limited by the stochastic nature of the underlying biochemical process. We develop a novel graphical representa...
Sang Hyun Lee, Manohar Shamaiah, Haris Vikalo
SAC
2008
ACM
13 years 7 months ago
Bayesian inference for a discretely observed stochastic kinetic model
The ability to infer parameters of gene regulatory networks is emerging as a key problem in systems biology. The biochemical data are intrinsically stochastic and tend to be observ...
Richard J. Boys, Darren J. Wilkinson, Thomas B. L....
CDC
2010
IEEE
141views Control Systems» more  CDC 2010»
13 years 2 months ago
Hybrid moment computation algorithm for biochemical reaction networks
Moment computation is essential to the analysis of stochastic kinetic models of biochemical reaction networks. It is often the case that the moment evolution, usually the first and...
Yun-Bo Zhao, Jongrae Kim, João Pedro Hespan...
CMSB
2007
Springer
14 years 1 months ago
A Unifying Framework for Modelling and Analysing Biochemical Pathways Using Petri Nets
We give a description of a Petri net-based framework for modelling and analysing biochemical pathways, which unifies the qualitative, stochastic and continuous paradigms. Each per...
David Gilbert, Monika Heiner, Sebastian Lehrack
BMCBI
2010
175views more  BMCBI 2010»
13 years 7 months ago
Global parameter estimation methods for stochastic biochemical systems
Background: The importance of stochasticity in cellular processes having low number of molecules has resulted in the development of stochastic models such as chemical master equat...
Suresh Kumar Poovathingal, Rudiyanto Gunawan