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» Synthetic biology: from modules to systems
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BMCBI
2010
142views more  BMCBI 2010»
13 years 7 months ago
Discover Protein Complexes in Protein-Protein Interaction Networks Using Parametric Local Modularity
Background: Recent advances in proteomic technologies have enabled us to create detailed protein-protein interaction maps in multiple species and in both normal and diseased cells...
Jongkwang Kim, Kai Tan
BMCBI
2006
169views more  BMCBI 2006»
13 years 7 months ago
Assessing protein similarity with Gene Ontology and its use in subnuclear localization prediction
Background: The accomplishment of the various genome sequencing projects resulted in accumulation of massive amount of gene sequence information. This calls for a large-scale comp...
Zhengdeng Lei, Yang Dai
JMLR
2006
169views more  JMLR 2006»
13 years 7 months ago
Bayesian Network Learning with Parameter Constraints
The task of learning models for many real-world problems requires incorporating domain knowledge into learning algorithms, to enable accurate learning from a realistic volume of t...
Radu Stefan Niculescu, Tom M. Mitchell, R. Bharat ...
CIG
2005
IEEE
14 years 1 months ago
Forcing Neurocontrollers to Exploit Sensory Symmetry Through Hard-wired Modularity in the Game of Cellz
Several attempts have been made in the past to construct encoding schemes that allow modularity to emerge in evolving systems, but success is limited. We believe that in order to c...
Julian Togelius, Simon M. Lucas
BMCBI
2010
76views more  BMCBI 2010»
13 years 7 months ago
Validation and characterization of DNA microarray gene expression data distribution and associated moments
Background: The data from DNA microarrays are increasingly being used in order to understand effects of different conditions, exposures or diseases on the modulation of the expres...
Reuben Thomas, Luis de la Torre, Xiaoqing Chang, S...