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BMCBI
2008
135views more  BMCBI 2008»
13 years 8 months ago
Ab-origin: an enhanced tool to identify the sourcing gene segments in germline for rearranged antibodies
Background: In the adaptive immune system, variable regions of immunoglobulin (IG) are encoded by random recombination of variable (V), diversity (D), and joining (J) gene segment...
Xiaojing Wang, Di Wu, SiYuan Zheng, Jing Sun, Lin ...
BMCBI
2008
99views more  BMCBI 2008»
13 years 8 months ago
Exhaustive prediction of disease susceptibility to coding base changes in the human genome
Background: Single Nucleotide Polymorphisms (SNPs) are the most abundant form of genomic variation and can cause phenotypic differences between individuals, including diseases. Ba...
Vinayak Kulkarni, Mounir Errami, Robert Barber, Ha...
BMCBI
2008
116views more  BMCBI 2008»
13 years 8 months ago
Gene Ontology annotations: what they mean and where they come from
To address the challenges of information integration and retrieval, the computational genomics community increasingly has come to rely on the methodology of creating annotations o...
David P. Hill, Barry Smith, Monica S. McAndrews-Hi...
BMCBI
2008
79views more  BMCBI 2008»
13 years 8 months ago
In silico docking of urokinase plasminogen activator and integrins
Background: Urokinase, its receptor and the integrins are functionally associated and involved in regulation of cell signaling, migration, adhesion and proliferation. No structura...
Bernard Degryse, Juan Fernández-Recio, Vale...
CN
2008
100views more  CN 2008»
13 years 8 months ago
Building resilient low-diameter peer-to-peer topologies
As more applications rely on underlying peer-to-peer topologies, the need for efficient and resilient infrastructure has become more pressing. A number of important classes of top...
Rita H. Wouhaybi, Andrew T. Campbell
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