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» Systematic calibration of a cell signaling network model
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RECOMB
2012
Springer
11 years 10 months ago
Reconstructing Boolean Models of Signaling
Abstract. Since the first emergence of protein-protein interaction networks, more than a decade ago, they have been viewed as static scaffolds of the signaling-regulatory events ...
Roded Sharan, Richard M. Karp
ICCS
2007
Springer
14 years 1 months ago
A Multiscale, Cell-Based Framework for Modeling Cancer Development
We use a systems approach to develop a predictive model that medical researchers can use to study and treat cancerous tumors. Our multiscale, cell-based model includes intracellula...
Yi Jiang
CIBCB
2007
IEEE
14 years 1 months ago
Spectral Decomposition of Signaling Networks
—Many dynamical processes can be represented as directed attributed graphs or Petri nets where relationships between various entities are explicitly expressed. Signaling networks...
Bahram Parvin, Nirmalya Ghosh, Laura Heiser, Merri...
BMCBI
2006
122views more  BMCBI 2006»
13 years 7 months ago
A domain-oriented approach to the reduction of combinatorial complexity in signal transduction networks
Background:Receptors and scaffold proteins possess a number of distinct domains and bind multiple partners. A common problem in modeling signaling systems arises from a combinator...
Holger Conzelmann, Julio Saez-Rodriguez, Thomas Sa...
NIPS
2003
13 years 9 months ago
GPPS: A Gaussian Process Positioning System for Cellular Networks
In this article, we present a novel approach to solving the localization problem in cellular networks. The goal is to estimate a mobile user’s position, based on measurements of...
Anton Schwaighofer, Marian Grigoras, Volker Tresp,...