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BMCBI
2008
108views more  BMCBI 2008»
13 years 8 months ago
Supervised Lowess normalization of comparative genome hybridization data - application to lactococcal strain comparisons
Background: Array-based comparative genome hybridization (aCGH) is commonly used to determine the genomic content of bacterial strains. Since prokaryotes in general have less cons...
Sacha A. F. T. van Hijum, Richard J. S. Baerends, ...
BMCBI
2005
135views more  BMCBI 2005»
13 years 8 months ago
A robust two-way semi-linear model for normalization of cDNA microarray data
Background: Normalization is a basic step in microarray data analysis. A proper normalization procedure ensures that the intensity ratios provide meaningful measures of relative e...
Deli Wang, Jian Huang, Hehuang Xie, Liliana Manzel...
GCB
2003
Springer
105views Biometrics» more  GCB 2003»
14 years 1 months ago
In silico prediction of UTR repeats using clustered EST data
Clustering of EST data is a method for the non-redundant representation of an organisms transcriptome. During clustering of large amounts of EST data, usually some large clusters ...
Stefan A. Rensing, Daniel Lang, Ralf Reski
JCB
2008
90views more  JCB 2008»
13 years 8 months ago
A Simple Model of the Modular Structure of Transcriptional Regulation in Yeast
Resolving the general organizational principles that govern the interactions during transcriptional gene regulation has great relevance for understanding disease progression, biof...
Vladimir Filkov, Nameeta Shah
GCB
2008
Springer
103views Biometrics» more  GCB 2008»
13 years 9 months ago
Utilizing Promoter Pair Orientations for HMM-based Analysis of ChIP-chip Data
: Array-based analysis of chromatin immunoprecipitation data (ChIP-chip) is a powerful technique for identifying DNA target regions of individual transcription factors. Here, we pr...
Michael Seifert, Jens Keilwagen, Marc Strickert, I...