Transcription factors (TFs) play key roles in controlling gene expression. Systematic identification and annotation of TFs, followed by construction of TF databases may serve as u...
Anyuan Guo, Xin Chen, Ge Gao, He Zhang, Qihui Zhu,...
Background: In the Bioinformatics field, a great deal of interest has been given to Non-negative matrix factorization technique (NMF), due to its capability of providing new insig...
Alberto D. Pascual-Montano, Pedro Carmona-Saez, Mo...
Background: Evolutionary conservation of RNA secondary structure is a typical feature of many functional non-coding RNAs. Since almost all of the available methods used for predic...
Andreas R. Gruber, Stephan H. F. Bernhart, Ivo L. ...
Abstract. Hierarchical classification problems gained increasing attention within the machine learning community, and several methods for hierarchically structured taxonomies have...
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...