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» Systems biology, models, and concurrency
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SIAMSC
2008
149views more  SIAMSC 2008»
13 years 9 months ago
Adaptive Discrete Galerkin Methods Applied to the Chemical Master Equation
In systems biology, the stochastic description of biochemical reaction kinetics is increasingly being employed to model gene regulatory networks and signalling pathways. Mathematic...
Peter Deuflhard, Wilhelm Huisinga, T. Jahnke, Mich...
ICPPW
2009
IEEE
13 years 7 months ago
A Scalable Parallel Approach for Peptide Identification from Large-Scale Mass Spectrometry Data
Identifying peptides, which are short polymeric chains of amino acid residues in a protein sequence, is of fundamental importance in systems biology research. The most popular appr...
Gaurav Ramesh Kulkarni, Ananth Kalyanaraman, Willi...
CONNECTION
2010
144views more  CONNECTION 2010»
13 years 7 months ago
The roles of the amygdala in the affective regulation of body, brain, and behaviour
Abstract. Despite the great amount of knowledge produced by the neuroscientific literature affective phenomena, current models tackling noncognitive aspects of behavior are often b...
Marco Mirolli, Francesco Mannella, Gianluca Baldas...
BMCBI
2011
13 years 1 months ago
To aggregate or not to aggregate high-dimensional classifiers
Background: High-throughput functional genomics technologies generate large amount of data with hundreds or thousands of measurements per sample. The number of sample is usually m...
Cheng-Jian Xu, Huub C. J. Hoefsloot, Age K. Smilde
BMCBI
2010
156views more  BMCBI 2010»
13 years 10 months ago
Adaptive coarse-grained Monte Carlo simulation of reaction and diffusion dynamics in heterogeneous plasma membranes
Background: An adaptive coarse-grained (kinetic) Monte Carlo (ACGMC) simulation framework is applied to reaction and diffusion dynamics in inhomogeneous domains. The presented mod...
Stuart Collins, Michail Stamatakis, Dionisios G. V...