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BMCBI
2006
113views more  BMCBI 2006»
13 years 8 months ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida
GECCO
2007
Springer
437views Optimization» more  GECCO 2007»
14 years 2 months ago
A gestalt genetic algorithm: less details for better search
The basic idea to defend in this paper is that an adequate perception of the search space, sacrificing most of the precision, can paradoxically accelerate the discovery of the mo...
Christophe Philemotte, Hugues Bersini
SAC
2009
ACM
14 years 2 months ago
Using geo-spatial session tagging for smart multicast session discovery
IP multicast is increasingly seen as efficient mode of live content distribution in the Internet to significantly large subscriber bases. Despite its numerous benefits over IP u...
Piyush Harsh, Richard Newman
IMSCCS
2006
IEEE
14 years 1 months ago
Combining Comparative Genomics with de novo Motif Discovery to Identify Human Transcription Factor DNA-Binding Motifs
Background: As more and more genomes are sequenced, comparative genomics approaches provide a methodology for identifying conserved regulatory elements that may be involved in gen...
Linyong Mao, W. Jim Zheng
VLDB
1999
ACM
140views Database» more  VLDB 1999»
14 years 4 days ago
Distributed Hypertext Resource Discovery Through Examples
We describe the architecture of a hypertext resource discovery system using a relational database. Such a system can answer questions that combine page contents, metadata, and hyp...
Soumen Chakrabarti, Martin van den Berg, Byron Dom