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BMCBI
2006
13 years 8 months ago
2006
Background: Existing tools for multiple-sequence alignment focus on aligning protein sequence or protein-coding DNA sequence, and are often based on extensions to Needleman-Wunsch...
BMCBI
2006
13 years 8 months ago
2006
Background: Protein sequence clustering has been widely used as a part of the analysis of protein structure and function. In most cases single linkage or graph-based clustering al...
BMCBI
2006
13 years 8 months ago
2006
Background: The goal of most microarray studies is either the identification of genes that are most differentially expressed or the creation of a good classification rule. The dis...
BMCBI
2006
13 years 8 months ago
2006
Background: Proteins are comprised of one or several building blocks, known as domains. Such domains can be classified into families according to their evolutionary origin. Wherea...
BMCBI
2006
13 years 8 months ago
2006
Affymetrix microarrays have become a standard experimental platform for studies of mRNA expression profiling. Their success is due, in part, to the multiple oligonucleotide featur...