In this paper, we generalize the notion of persistence, which has been originally introduced for two-dimensional formations, to Rd for d 3, seeking to provide a theoretical framew...
Changbin Yu, Julien M. Hendrickx, Baris Fidan, Bri...
Background: The availability of various "omics" datasets creates a prospect of performing the study of genomewide genetic regulatory networks. However, one of the major ...
Background: Prediction of catalytic residues is a major step in characterizing the function of enzymes. In its simpler formulation, the problem can be cast into a binary classific...
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...