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AUTOMATICA
2007
88views more  AUTOMATICA 2007»
13 years 7 months ago
Three and higher dimensional autonomous formations: Rigidity, persistence and structural persistence
In this paper, we generalize the notion of persistence, which has been originally introduced for two-dimensional formations, to Rd for d 3, seeking to provide a theoretical framew...
Changbin Yu, Julien M. Hendrickx, Baris Fidan, Bri...
BMCBI
2010
160views more  BMCBI 2010»
13 years 7 months ago
Quantitative model for inferring dynamic regulation of the tumour suppressor gene p53
Background: The availability of various "omics" datasets creates a prospect of performing the study of genomewide genetic regulatory networks. However, one of the major ...
Junbai Wang, Tianhai Tian
BMCBI
2010
129views more  BMCBI 2010»
13 years 7 months ago
Automatic prediction of catalytic residues by modeling residue structural neighborhood
Background: Prediction of catalytic residues is a major step in characterizing the function of enzymes. In its simpler formulation, the problem can be cast into a binary classific...
Elisa Cilia, Andrea Passerini
BMCBI
2010
179views more  BMCBI 2010»
13 years 7 months ago
A semi-supervised learning approach to predict synthetic genetic interactions by combining functional and topological properties
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
Zhuhong You, Zheng Yin, Kyungsook Han, De-Shuang H...
BMCBI
2010
105views more  BMCBI 2010»
13 years 7 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang
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