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BMCBI
2008
150views more  BMCBI 2008»
13 years 8 months ago
MOSAIC: an online database dedicated to the comparative genomics of bacterial strains at the intra-species level
Background: The recent availability of complete sequences for numerous closely related bacterial genomes opens up new challenges in comparative genomics. Several methods have been...
Hélène Chiapello, Annie Gendrault, C...
BMCBI
2008
136views more  BMCBI 2008»
13 years 8 months ago
An efficient method for the prediction of deleterious multiple-point mutations in the secondary structure of RNAs using suboptim
Background: RNAmute is an interactive Java application which, given an RNA sequence, calculates the secondary structure of all single point mutations and organizes them into categ...
Alexander Churkin, Danny Barash
BMCBI
2008
135views more  BMCBI 2008»
13 years 8 months ago
Ab-origin: an enhanced tool to identify the sourcing gene segments in germline for rearranged antibodies
Background: In the adaptive immune system, variable regions of immunoglobulin (IG) are encoded by random recombination of variable (V), diversity (D), and joining (J) gene segment...
Xiaojing Wang, Di Wu, SiYuan Zheng, Jing Sun, Lin ...
BMCBI
2008
100views more  BMCBI 2008»
13 years 8 months ago
Hotspot Hunter: a computational system for large-scale screening and selection of candidate immunological hotspots in pathogen p
Background: T-cell epitopes that promiscuously bind to multiple alleles of a human leukocyte antigen (HLA) supertype are prime targets for development of vaccines and immunotherap...
Guanglan Zhang, Asif M. Khan, Kellathur N. Sriniva...
CBRMD
2008
167views more  CBRMD 2008»
13 years 8 months ago
Case-based Reasoning for Diagnosis of Stress using Enhanced Cosine and Fuzzy Similarity
Intelligent analysis of heterogeneous data and information sources for efficient decision support presents an interesting yet challenging task in clinical environments. This is par...
Mobyen Uddin Ahmed, Shahina Begum, Peter Funk, Nin...
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