Background: Protein loops encompass 50% of protein residues in available three-dimensional structures. These regions are often involved in protein functions, e.g. binding site, ca...
Background: Structural variations caused by a wide range of physico-chemical and biological sources directly influence the function of a protein. For enzymatic proteins, the struc...
Drew H. Bryant, Mark Moll, Brian Y. Chen, Viachesl...
Background: In recent years, the number of available RNA structures has rapidly grown reflecting the increased interest on RNA biology. Similarly to the studies carried out two de...
The development of high-throughput genome sequencing and protein structure determination techniques have provided researchers with a wealth of biological data. Integrated analysis...
William M. Shui, Raymond K. Wong, Stephen C. Graha...
Understanding the functional significance of alternative splicing and other mechanisms that generate RNA transcript diversity is an important challenge facing modern-day molecular...
Ann E. Loraine, Gregg A. Helt, Melissa S. Cline, M...