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» The ASTRAL compendium for protein structure and sequence ana...
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CIBCB
2005
IEEE
14 years 1 months ago
Toward Protein Structure Analysis with Self-Organizing Maps
- Establishing structure-function relationships on the proteomic scale is a unique challenge faced by bioinformatics and molecular biosciences. Large protein families represent nat...
Lutz Hamel, Gongqin Sun, Jing Zhang
BMCBI
2005
97views more  BMCBI 2005»
13 years 7 months ago
Sequence variation in ligand binding sites in proteins
Background: The recent explosion in the availability of complete genome sequences has led to the cataloging of tens of thousands of new proteins and putative proteins. Many of the...
Thomas J. Magliery, Lynne Regan
BIOCOMP
2006
13 years 8 months ago
TALI: Protein Structure Alignment Using Backbone Torsion Angles
- This article introduces a novel protein structure alignment method (named TALI) based on protein backbone torsion angle instead of the more traditional distance matrix. Represent...
Xijiang Miao, Michael Bryson, Homayoun Valafar
BMCBI
2010
137views more  BMCBI 2010»
13 years 7 months ago
Improving pairwise sequence alignment accuracy using near-optimal protein sequence alignments
Background: While the pairwise alignments produced by sequence similarity searches are a powerful tool for identifying homologous proteins - proteins that share a common ancestor ...
Michael L. Sierk, Michael E. Smoot, Ellen J. Bass,...
CSB
2005
IEEE
115views Bioinformatics» more  CSB 2005»
14 years 1 months ago
Mining Protein Sequence Motifs Representing Common 3D Structures
Understanding the relationship between protein structure and its sequence is one of the most important tasks of current bioinformatics research. In this work, recurring protein se...
Wei Zhong, Gulsah Altun, Robert W. Harrison, Phang...