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KRDB
1994
78views Database» more  KRDB 1994»
13 years 9 months ago
The Problems of Data Modeling in Software Practice
This paper presents, fromthe author's perspective, the problems that occur in practice during data modelling. The author's experiences are a result of a considerable num...
Harald Huber
BIBM
2007
IEEE
133views Bioinformatics» more  BIBM 2007»
13 years 8 months ago
Mining Clinical Data with a Temporal Dimension: A Case Study
Clinical databases store large amounts of information about patients and their medical conditions. Data mining techniques can extract relationships and patterns holding in this we...
Michele Berlingerio, Francesco Bonchi, Fosca Giann...
BMCBI
2010
191views more  BMCBI 2010»
13 years 8 months ago
BiGG: a Biochemical Genetic and Genomic knowledgebase of large scale metabolic reconstructions
Background: Genome-scale metabolic reconstructions under the Constraint Based Reconstruction and Analysis (COBRA) framework are valuable tools for analyzing the metabolic capabili...
Jan Schellenberger, Junyoung O. Park, Tom M. Conra...
BMCBI
2010
175views more  BMCBI 2010»
13 years 8 months ago
Global parameter estimation methods for stochastic biochemical systems
Background: The importance of stochasticity in cellular processes having low number of molecules has resulted in the development of stochastic models such as chemical master equat...
Suresh Kumar Poovathingal, Rudiyanto Gunawan
BMCBI
2008
85views more  BMCBI 2008»
13 years 8 months ago
Normalizing biomedical terms by minimizing ambiguity and variability
Background: One of the difficulties in mapping biomedical named entities, e.g. genes, proteins, chemicals and diseases, to their concept identifiers stems from the potential varia...
Yoshimasa Tsuruoka, John McNaught, Sophia Ananiado...