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BMCBI
2010
118views more  BMCBI 2010»
13 years 11 months ago
Testing for mean and correlation changes in microarray experiments: an application for pathway analysis
Background: Microarray experiments examine the change in transcript levels of tens of thousands of genes simultaneously. To derive meaningful data, biologists investigate the resp...
Mayer Alvo, Zhongzhu Liu, Andrew Williams, Carole ...
BMCBI
2010
138views more  BMCBI 2010»
13 years 11 months ago
A database and API for variation, dense genotyping and resequencing data
Background: Advances in sequencing and genotyping technologies are leading to the widespread availability of multi-species variation data, dense genotype data and large-scale rese...
Daniel Rios, William M. McLaren, Yuan Chen, Ewan B...
BMCBI
2010
113views more  BMCBI 2010»
13 years 11 months ago
Gene prioritization and clustering by multi-view text mining
Background: Text mining has become a useful tool for biologists trying to understand the genetics of diseases. In particular, it can help identify the most interesting candidate g...
Shi Yu, Léon-Charles Tranchevent, Bart De M...
BMCBI
2010
131views more  BMCBI 2010»
13 years 11 months ago
A comparison of approximation techniques for variance-based sensitivity analysis of biochemical reaction systems
Background: Sensitivity analysis is an indispensable tool for the analysis of complex systems. In a recent paper, we have introduced a thermodynamically consistent variance-based ...
Hong-Xuan Zhang, John Goutsias
BMCBI
2010
126views more  BMCBI 2010»
13 years 11 months ago
A boosting method for maximizing the partial area under the ROC curve
Background: The receiver operating characteristic (ROC) curve is a fundamental tool to assess the discriminant performance for not only a single marker but also a score function c...
Osamu Komori, Shinto Eguchi