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WOA
2010
13 years 6 months ago
A Self-Organising Infrastructure for Chemical-Semantic Coordination: Experiments in TuCSoN
Abstract--Recent works proposed the adoption of a natureinspired approach of chemistry for implementing service architectures suitable for pervasive applications [34]. In particula...
Elena Nardini, Mirko Viroli, Matteo Casadei, Andre...
BCSHCI
2008
13 years 10 months ago
Low cost prototyping: part 1, or how to produce better ideas faster by getting user reactions early and often
Although approaches to User Centered Software Development have existed for almost 20 years a rift still exists between theory and practice. In practice, many software projects are...
Stephen Brown, Andreas Holzinger
BMCBI
2010
133views more  BMCBI 2010»
13 years 8 months ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang
BIOCOMP
2010
13 years 6 months ago
A Model Reduction Technique for Stochastic Biochemical Kinetics
Abstract-- Modeling the intermolecular reactions in a single cell is a critical problem in computational biology. Biochemical reaction systems often involve species in both low and...
Silvana Ilie, Ekaterina Kudashkina
BIBE
2006
IEEE
137views Bioinformatics» more  BIBE 2006»
14 years 2 months ago
Leveraging Chemical Background Knowledge for the Prediction of Growth Inhibition
We show how chemical background knowledge can be used to improve the prediction performance in structureactivitity relationships (SARs) for non-congeneric compounds. The goal of t...
Lothar Richter, Stefan Hechtl, Stefan Kramer