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» The Complexity of Futile Questioning
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BMCBI
2005
100views more  BMCBI 2005»
13 years 7 months ago
Speeding disease gene discovery by sequence based candidate prioritization
Background: Regions of interest identified through genetic linkage studies regularly exceed 30 centimorgans in size and can contain hundreds of genes. Traditionally this number is...
Euan A. Adie, Richard R. Adams, Kathryn L. Evans, ...
BMCBI
2005
152views more  BMCBI 2005»
13 years 7 months ago
CoPub Mapper: mining MEDLINE based on search term co-publication
Background: High throughput microarray analyses result in many differentially expressed genes that are potentially responsible for the biological process of interest. In order to ...
Blaise T. F. Alako, Antoine Veldhoven, Sjozef van ...
BMCBI
2005
163views more  BMCBI 2005»
13 years 7 months ago
Alkahest NuclearBLAST: a user-friendly BLAST management and analysis system
Background -: Sequencing of EST and BAC end datasets is no longer limited to large research groups. Drops in per-base pricing have made high throughput sequencing accessible to in...
Stephen E. Diener, Thomas D. Houfek, Sam E. Kalat,...
BMCBI
2005
124views more  BMCBI 2005»
13 years 7 months ago
ErmineJ: Tool for functional analysis of gene expression data sets
Background: It is common for the results of a microarray study to be analyzed in the context of biologically-motivated groups of genes such as pathways or Gene Ontology categories...
Homin K. Lee, William Braynen, Kiran Keshav, Paul ...
BMCBI
2005
163views more  BMCBI 2005»
13 years 7 months ago
CoaSim: A flexible environment for simulating genetic data under coalescent models
Background: Coalescent simulations are playing a large role in interpreting large scale intraspecific sequence or polymorphism surveys and for planning and evaluating association ...
Thomas Mailund, Mikkel H. Schierup, Christian N. S...