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» The Complexity of Global Constraints
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AAAI
2000
13 years 9 months ago
Iterative Flattening: A Scalable Method for Solving Multi-Capacity Scheduling Problems
One challenge for research in constraint-based scheduling has been to produce scalable solution procedures under fairly general representational assumptions. Quite often, the comp...
Amedeo Cesta, Angelo Oddi, Stephen F. Smith
IJCAI
1993
13 years 9 months ago
Provably Bounded Optimal Agents
Since its inception, arti cial intelligence has relied upon a theoretical foundation centred around perfect rationality as the desired property of intelligent systems. We argue, a...
Stuart J. Russell, Devika Subramanian, Ronald Parr
BMCBI
2010
84views more  BMCBI 2010»
13 years 8 months ago
A variational Bayes algorithm for fast and accurate multiple locus genome-wide association analysis
Background: The success achieved by genome-wide association (GWA) studies in the identification of candidate loci for complex diseases has been accompanied by an inability to expl...
Benjamin A. Logsdon, Gabriel E. Hoffman, Jason G. ...
BMCBI
2010
109views more  BMCBI 2010»
13 years 8 months ago
Prediction of the binding affinities of peptides to class II MHC using a regularized thermodynamic model
Background: The binding of peptide fragments of extracellular peptides to class II MHC is a crucial event in the adaptive immune response. Each MHC allotype generally binds a dist...
Andrew J. Bordner, Hans D. Mittelmann
BMCBI
2008
178views more  BMCBI 2008»
13 years 8 months ago
Identification of coherent patterns in gene expression data using an efficient biclustering algorithm and parallel coordinate vi
Background: The DNA microarray technology allows the measurement of expression levels of thousands of genes under tens/hundreds of different conditions. In microarray data, genes ...
Kin-On Cheng, Ngai-Fong Law, Wan-Chi Siu, Alan Wee...