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» The Complexity of Polynomial-Time Approximation
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BMCBI
2010
178views more  BMCBI 2010»
13 years 7 months ago
Selecting high-dimensional mixed graphical models using minimal AIC or BIC forests
Background: Chow and Liu showed that the maximum likelihood tree for multivariate discrete distributions may be found using a maximum weight spanning tree algorithm, for example K...
David Edwards, Gabriel C. G. de Abreu, Rodrigo Lab...
BMCBI
2010
154views more  BMCBI 2010»
13 years 7 months ago
Binary image representation of a ligand binding site: its application to efficient sampling of a conformational ensemble
Background: Modelling the ligand binding site of a protein is an important component of understanding proteinligand interactions and is being actively studied. Even if the side ch...
Edon Sung, Sangsoo Kim, Whanchul Shin
BMCBI
2010
138views more  BMCBI 2010»
13 years 7 months ago
UFFizi: a generic platform for ranking informative features
Background: Feature selection is an important pre-processing task in the analysis of complex data. Selecting an appropriate subset of features can improve classification or cluste...
Assaf Gottlieb, Roy Varshavsky, Michal Linial, Dav...
BMCBI
2008
140views more  BMCBI 2008»
13 years 7 months ago
Improved accuracy of multiple ncRNA alignment by incorporating structural information into a MAFFT-based framework
Background: Structural alignment of RNAs is becoming important, since the discovery of functional non-coding RNAs (ncRNAs). Recent studies, mainly based on various approximations ...
Kazutaka Katoh, Hiroyuki Toh
BMCBI
2008
242views more  BMCBI 2008»
13 years 7 months ago
New time-scale criteria for model simplification of bio-reaction systems
Background: Quasi-steady state approximation (QSSA) based on time-scale analysis is known to be an effective method for simplifying metabolic reaction system, but the conventional...
Junwon Choi, Kyung-won Yang, Tai-yong Lee, Sang Yu...