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» The Complexity of the Single Individual SNP Haplotyping Prob...
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BMCBI
2006
134views more  BMCBI 2006»
13 years 7 months ago
Application of machine learning in SNP discovery
Background: Single nucleotide polymorphisms (SNP) constitute more than 90% of the genetic variation, and hence can account for most trait differences among individuals in a given ...
Lakshmi K. Matukumalli, John J. Grefenstette, Davi...
BCB
2010
161views Bioinformatics» more  BCB 2010»
13 years 2 months ago
Genome-wide compatible SNP intervals and their properties
Recent studies suggest that the mammalian genomes can be subdivided in segments within which there is limited haplotype diversity. Understanding the distribution and structure of ...
Jeremy W. Wang, Kyle J. Moore, Qi Zhang, Fernando ...
BMCBI
2005
157views more  BMCBI 2005»
13 years 7 months ago
Decision Forest Analysis of 61 Single Nucleotide Polymorphisms in a Case-Control Study of Esophageal Cancer; a novel method
Background: Systematic evaluation and study of single nucleotide polymorphisms (SNPs) made possible by high throughput genotyping technologies and bioinformatics promises to provi...
Qian Xie, Luke D. Ratnasinghe, Huixiao Hong, Roger...
BMCBI
2006
169views more  BMCBI 2006»
13 years 7 months ago
Comparative analysis of haplotype association mapping algorithms
Background: Finding the genetic causes of quantitative traits is a complex and difficult task. Classical methods for mapping quantitative trail loci (QTL) in miceuse an F2 cross b...
Phillip McClurg, Mathew T. Pletcher, Tim Wiltshire...
BMCBI
2004
133views more  BMCBI 2004»
13 years 7 months ago
Artificial neural network approach for selection of susceptible single nucleotide polymorphisms and construction of prediction m
Background: Screening of various gene markers such as single nucleotide polymorphism (SNP) and correlation between these markers and development of multifactorial disease have pre...
Yasuyuki Tomita, Shuta Tomida, Yuko Hasegawa, Yoic...