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    BMCBI
    2006
    101views more  BMCBI 2006»
    SuperMimic - Fitting peptide mimetics into protein structures
    13 years 7 months ago
    SuperMimic - Fitting peptide mimetics into protein structures
    Download  bioinformatics.charite.de
    Background: Various experimental techniques yield peptides that are biologically active but have unfavourable pharmacological properties. The design of structurally similar organi...
    Andrean Goede, Elke Michalsky, Ulrike Schmidt, Rob...
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    BMCBI
    2006
    179views more  BMCBI 2006»
    Multiscale Hy3S: Hybrid stochastic simulation for supercomputers
    13 years 7 months ago
    Multiscale Hy3S: Hybrid stochastic simulation for supercomputers
    Download  www.dtc.umn.edu
    Background: Stochastic simulation has become a useful tool to both study natural biological systems and design new synthetic ones. By capturing the intrinsic molecular fluctuation...
    Howard Salis, Vassilios Sotiropoulos, Yiannis N. K...
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    BMCBI
    2006
    160views more  BMCBI 2006»
    Gene prediction in eukaryotes with a generalized hidden Markov model that uses hints from external sources
    13 years 7 months ago
    Gene prediction in eukaryotes with a generalized hidden Markov model that uses hints from external sources
    Download  www.biomedcentral.com
    Background: In order to improve gene prediction, extrinsic evidence on the gene structure can be collected from various sources of information such as genome-genome comparisons an...
    Mario Stanke, Oliver Schöffmann, Burkhard Mor...
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    BMCBI
    2006
    201views more  BMCBI 2006»
    Gene selection algorithms for microarray data based on least squares support vector machine
    13 years 7 months ago
    Gene selection algorithms for microarray data based on least squares support vector machine
    Download  www.biomedcentral.com
    Background: In discriminant analysis of microarray data, usually a small number of samples are expressed by a large number of genes. It is not only difficult but also unnecessary ...
    E. Ke Tang, Ponnuthurai N. Suganthan, Xin Yao
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    BMCBI
    2006
    108views more  BMCBI 2006»
    RibAlign: a software tool and database for eubacterial phylogeny based on concatenated ribosomal protein subunits
    13 years 7 months ago
    RibAlign: a software tool and database for eubacterial phylogeny based on concatenated ribosomal protein subunits
    Download  www.biomedcentral.com
    Background: Until today, analysis of 16S ribosomal RNA (rRNA) sequences has been the de-facto gold standard for the assessment of phylogenetic relationships among prokaryotes. How...
    Hanno Teeling, Frank Oliver Glöckner
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