84 search results - page 5 / 17 » The Context-Dependence of Amino Acid Properties |
BMCBI
2006
2006
Searching for interpretable rules for disease mutations: a simulated annealing bump hunting strategy
13 years 7 months ago
Background: Understanding how amino acid substitutions affect protein functions is critical for the study of proteins and their implications in diseases. Although methods have bee...
BMCBI
2005
13 years 7 months ago
2005
Background: Protein subcellular localization is an important determinant of protein function and hence, reliable methods for prediction of localization are needed. A number of pre...
BICOB
2009
Springer
14 years 2 months ago
2009
Springer
Here we present a simple method based on graph spectral properties to automatically partition multi-domain proteins into individual domains. The identification of structural domain...
BMCBI
2010
13 years 7 months ago
2010
Background: Codon substitution constitutes a fundamental process in molecular biology that has been studied extensively. However, prior studies rely on various assumptions, e.g. r...
BMCBI
2004
13 years 7 months ago
2004
Background: Accessible surface area (ASA) or solvent accessibility of amino acids in a protein has important implications. Knowledge of surface residues helps in locating potentia...