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BMCBI
2010
104views more  BMCBI 2010»
13 years 9 months ago
Parameters for accurate genome alignment
Background: Genome sequence alignments form the basis of much research. Genome alignment depends on various mundane but critical choices, such as how to mask repeats and which sco...
Martin C. Frith, Michiaki Hamada, Paul Horton
BMCBI
2010
124views more  BMCBI 2010»
13 years 9 months ago
Estimation and efficient computation of the true probability of recurrence of short linear protein sequence motifs in unrelated
Background: Large datasets of protein interactions provide a rich resource for the discovery of Short Linear Motifs (SLiMs) that recur in unrelated proteins. However, existing met...
Norman E. Davey, Richard J. Edwards, Denis C. Shie...
BIOINFORMATICS
2007
195views more  BIOINFORMATICS 2007»
13 years 9 months ago
Context-dependent clustering for dynamic cellular state modeling of microarray gene expression
Motivation: High-throughput expression profiling allows researchers to study gene activities globally. Genes with similar expression profiles are likely to encode proteins that ma...
Shinsheng Yuan, Ker-Chau Li
BMCBI
2010
139views more  BMCBI 2010»
13 years 9 months ago
RNAstructure: software for RNA secondary structure prediction and analysis
Background: To understand an RNA sequence's mechanism of action, the structure must be known. Furthermore, target RNA structure is an important consideration in the design of...
Jessica S. Reuter, David H. Mathews
BMCBI
2010
137views more  BMCBI 2010»
13 years 9 months ago
TreeGraph 2: Combining and visualizing evidence from different phylogenetic analyses
Background: Today it is common to apply multiple potentially conflicting data sources to a given phylogenetic problem. At the same time, several different inference techniques are...
Ben C. Stöver, Kai F. Müller
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