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BMCBI
2011
13 years 2 months ago
A theoretical entropy score as a single value to express inhibitor selectivity
Background: Designing maximally selective ligands that act on individual targets is the dominant paradigm in drug discovery. Poor selectivity can underlie toxicity and side effect...
Joost C. M. Uitdehaag, Guido J. R. Zaman
ENVSOFT
2011
134views more  ENVSOFT 2011»
13 years 2 months ago
Modelling and simulation of a jet fan for controlled air flow in large enclosures
Jet fans are applied for control of air flow and support of pollutant dispersal in large enclosures. In The Netherlands, application is well known for car parks as part of the fir...
B. J. M. v. d. Giesen, S. H. A. Penders, M. G. L. ...
TASE
2011
IEEE
12 years 11 months ago
Fast Intersection-Free Offset Surface Generation From Freeform Models With Triangular Meshes
Abstract—A fast offset surface generation approach is presented in this paper to construct intersection-free offset surfaces, which preserve sharp features, from freeform triangu...
Shengjun Liu, Charlie C. L. Wang
BMCBI
2011
12 years 11 months ago
Combinatorial analysis and algorithms for quasispecies reconstruction using next-generation sequencing
Background: Next-generation sequencing (NGS) offers a unique opportunity for high-throughput genomics and has potential to replace Sanger sequencing in many fields, including de-n...
Mattia C. F. Prosperi, Luciano Prosperi, Alessandr...
BMCBI
2011
12 years 11 months ago
The Proteogenomic Mapping Tool
Background: High-throughput mass spectrometry (MS) proteomics data is increasingly being used to complement traditional structural genome annotation methods. To keep pace with the...
William S. Sanders, Nan Wang, Susan M. Bridges, Br...
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