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» The Distribution of Genomic Distance between Random Genomes
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RECOMB
2012
Springer
11 years 10 months ago
A Model for Biased Fractionation after Whole Genome Duplication
Background: Paralog reduction, the loss of duplicate genes after whole genome duplication (WGD) is a pervasive process. Whether this loss proceeds gene by gene or through deletion...
David Sankoff, Chunfang Zheng, Baoyong Wang
BMCBI
2008
132views more  BMCBI 2008»
13 years 7 months ago
The Average Mutual Information Profile as a Genomic Signature
Background: Occult organizational structures in DNA sequences may hold the key to understanding functional and evolutionary aspects of the DNA molecule. Such structures can also p...
Mark Bauer, Sheldon M. Schuster, Khalid Sayood
BMCBI
2010
95views more  BMCBI 2010»
13 years 7 months ago
Heuristics for the inversion median problem
Background: The study of genome rearrangements has become a mainstay of phylogenetics and comparative genomics. Fundamental in such a study is the median problem: given three geno...
Vaibhav Rajan, Andrew Wei Xu, Yu Lin, Krister M. S...
TREC
2004
13 years 9 months ago
Experience of Using SVM for the Triage Task in TREC 2004 Genomics Track
This paper reports our knowledge-ignorant machine learning approach to the triage task in TREC2004 genomics track, which is actually a text categorization problem. We applied Supp...
Dell Zhang, Wee Sun Lee
PSB
2003
13 years 9 months ago
MAP: Searching Large Genome Databases
A number of biological applications require comparison of large genome strings. Current techniques suffer from both disk I/O and computational cost because of extensive memory req...
Tamer Kahveci, Ambuj K. Singh