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BMCBI
2010
13 years 10 months ago
2010
Background: An important objective of DNA microarray-based gene expression experimentation is determining interrelationships that exist between differentially expressed genes and ...
BMCBI
2010
13 years 10 months ago
2010
Background: ChIP-Seq, which combines chromatin immunoprecipitation (ChIP) with high-throughput massively parallel sequencing, is increasingly being used for identification of prot...
BMCBI
2010
13 years 10 months ago
2010
Background: Phenomenological information about regulatory interactions is frequently available and can be readily converted to Boolean models. Fully quantitative models, on the ot...
BMCBI
2007
13 years 10 months ago
2007
Background: Experimental studies of gene expression have identified some of the individual molecular components and elementary reactions that comprise and control cellular behavio...
BMCBI
2008
13 years 10 months ago
2008
: The tumour suppressor protein p53 protein has a core domain that binds DNA and is the site for most oncogenic mutations. This domain is quite unstable compared to its homologs p...