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» The Expressive Power of Synchronizations
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BMCBI
2010
95views more  BMCBI 2010»
15 years 4 months ago
Modelling p-value distributions to improve theme-driven survival analysis of cancer transcriptome datasets
Background: Theme-driven cancer survival studies address whether the expression signature of genes related to a biological process can predict patient survival time. Although this...
Esteban Czwan, Benedikt Brors, David Kipling
130
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BMCBI
2008
83views more  BMCBI 2008»
15 years 4 months ago
Prioritization of gene regulatory interactions from large-scale modules in yeast
Background: The identification of groups of co-regulated genes and their transcription factors, called transcriptional modules, has been a focus of many studies about biological s...
Ho-Joon Lee, Thomas Manke, Ricardo Bringas, Martin...
BMCBI
2010
152views more  BMCBI 2010»
15 years 4 months ago
Comparative study of three commonly used continuous deterministic methods for modeling gene regulation networks
Background: A gene-regulatory network (GRN) refers to DNA segments that interact through their RNA and protein products and thereby govern the rates at which genes are transcribed...
Martin T. Swain, Johannes J. Mandel, Werner Dubitz...
165
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BMCBI
2008
118views more  BMCBI 2008»
15 years 4 months ago
PseudoGeneQuest - Service for identification of different pseudogene types in the human genome
Background: Pseudogenes, nonfunctional copies of genes, evolve fast due the lack of evolutionary pressures and thus appear in several different forms. PseudoGeneQuest is an online...
Csaba P. Ortutay, Mauno Vihinen
BMCBI
2010
114views more  BMCBI 2010»
15 years 4 months ago
Detecting variants with Metabolic Design, a new software tool to design probes for explorative functional DNA microarray develop
Background: Microorganisms display vast diversity, and each one has its own set of genes, cell components and metabolic reactions. To assess their huge unexploited metabolic poten...
Sébastien Terrat, Eric Peyretaillade, Olivi...