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» The Factor Graph Network Model for Biological Systems
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COCOA
2011
Springer
12 years 8 months ago
Algorithmic Aspects of Heterogeneous Biological Networks Comparison
Biological networks are commonly used to model molecular activity within the cell. Recent experimental studies have shown that the detection of conserved subnetworks across several...
Guillaume Blin, Guillaume Fertin, Hafedh Mohamed-B...
BIBM
2008
IEEE
175views Bioinformatics» more  BIBM 2008»
14 years 3 months ago
Integrative Protein Function Transfer Using Factor Graphs and Heterogeneous Data Sources
We propose a novel approach for predicting protein functions of an organism by coupling sequence homology and PPI data between two (or more) species with multifunctional Gene Onto...
Antonina Mitrofanova, Vladimir Pavlovic, Bud Mishr...
BMCBI
2004
104views more  BMCBI 2004»
13 years 8 months ago
Discriminative topological features reveal biological network mechanisms
Background: Recent genomic and bioinformatic advances have motivated the development of numerous network models intending to describe graphs of biological, technological, and soci...
Manuel Middendorf, Etay Ziv, Carter Adams, Jen Hom...
TVCG
2008
147views more  TVCG 2008»
13 years 8 months ago
Cerebral: Visualizing Multiple Experimental Conditions on a Graph with Biological Context
Systems biologists use interaction graphs to model the behavior of biological systems at the molecular level. In an iterative process, such biologists observe the reactions of livi...
Aaron Barsky, Tamara Munzner, Jennifer L. Gardy, R...
BMCBI
2010
97views more  BMCBI 2010»
13 years 8 months ago
Dual-functioning transcription factors in the developmental gene network of Drosophila melanogaster
Background: Quantitative models for transcriptional regulation have shown great promise for advancing our understanding of the biological mechanisms underlying gene regulation. Ho...
Denis C. Bauer, Fabian A. Buske, Timothy L. Bailey