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BMCBI
2010
112views more  BMCBI 2010»
13 years 10 months ago
Orientation-dependent backbone-only residue pair scoring functions for fixed backbone protein design
Background: Empirical scoring functions have proven useful in protein structure modeling. Most such scoring functions depend on protein side chain conformations. However, backbone...
Andrew J. Bordner
BMCBI
2008
134views more  BMCBI 2008»
13 years 10 months ago
Bioinformatic analyses of mammalian 5'-UTR sequence properties of mRNAs predicts alternative translation initiation sites
Background: Utilization of alternative initiation sites for protein translation directed by non-AUG codons in mammalian mRNAs is observed with increasing frequency. Alternative in...
Jill L. Wegrzyn, Thomas M. Drudge, Faramarz Valafa...
DATAMINE
2008
143views more  DATAMINE 2008»
13 years 10 months ago
Automatically countering imbalance and its empirical relationship to cost
Learning from imbalanced datasets presents a convoluted problem both from the modeling and cost standpoints. In particular, when a class is of great interest but occurs relatively...
Nitesh V. Chawla, David A. Cieslak, Lawrence O. Ha...
BMCBI
2006
133views more  BMCBI 2006»
13 years 10 months ago
An integrated approach to the prediction of domain-domain interactions
Background: The development of high-throughput technologies has produced several large scale protein interaction data sets for multiple species, and significant efforts have been ...
Hyunju Lee, Minghua Deng, Fengzhu Sun, Ting Chen
IS
2008
13 years 10 months ago
Conformance checking of processes based on monitoring real behavior
Many companies have adopted Process-aware Information Systems (PAIS) to support their business processes in some form. On the one hand these systems typically log events (e.g., in ...
Anne Rozinat, Wil M. P. van der Aalst