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IDA
2005
Springer
14 years 2 months ago
Biological Cluster Validity Indices Based on the Gene Ontology
With the invention of biotechnological high throughput methods like DNA microarrays and the analysis of the resulting huge amounts of biological data, clustering algorithms gain ne...
Nora Speer, Christian Spieth, Andreas Zell
CIKM
2005
Springer
14 years 2 months ago
Semantic similarity over the gene ontology: family correlation and selecting disjunctive ancestors
Many bioinformatics applications would benefit from comparing proteins based on their biological role rather than their sequence. In most biological databases, proteins are alrea...
Francisco M. Couto, Mário J. Silva, Pedro C...
TREC
2003
13 years 10 months ago
Searching for geneRIFs: Concept-Based Query Expansion and Bayes Classification
k gene annotations. Our indexing machinery produces per indexed MEDLINE abstract a list of concepts with an accompanying weight, termed a fingerprint. Searching is done by matching...
Rob Jelier, Martijn J. Schuemie, C. Christiaan van...
BMCBI
2010
144views more  BMCBI 2010»
13 years 8 months ago
Identifying overrepresented concepts in gene lists from literature: a statistical approach based on Poisson mixture model
Background: Large-scale genomic studies often identify large gene lists, for example, the genes sharing the same expression patterns. The interpretation of these gene lists is gen...
Xin He, Moushumi Sen Sarma, Xu Ling, Brant W. Chee...