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BMCBI
2010
123views more  BMCBI 2010»
13 years 2 months ago
Predicting conserved protein motifs with Sub-HMMs
Background: Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is th...
Kevin Horan, Christian R. Shelton, Thomas Girke
BIBM
2008
IEEE
125views Bioinformatics» more  BIBM 2008»
13 years 7 months ago
Systems Biology via Redescription and Ontologies (III): Protein Classification Using Malaria Parasite's Temporal Transcriptomic
This paper addresses the protein classification problem, and explores how its accuracy can be improved by using information from time-course gene expression data. The methods are ...
Antonina Mitrofanova, Samantha Kleinberg, Jane Car...
KDD
2001
ACM
163views Data Mining» more  KDD 2001»
14 years 8 months ago
Learning to recognize brain specific proteins based on low-level features from on-line prediction servers
During the last decade, the area of bioinformatics has produced an overwhelming amount of data, with the recently published draft of the human genome being the most prominent exam...
Henrik Boström, Joakim Cöster, Lars Aske...
IHI
2012
370views Healthcare» more  IHI 2012»
12 years 3 months ago
FUSE: a system for data-driven multi-level functional summarization of protein interaction networks
Despite recent progress in high-throughput experimental studies, systems level visualization and analysis of large protein interaction networks (ppi) remains a challenging task, g...
Boon-Siew Seah, Sourav S. Bhowmick, Charles Forbes...
BMCBI
2005
155views more  BMCBI 2005»
13 years 7 months ago
Mining protein function from text using term-based support vector machines
Background: Text mining has spurred huge interest in the domain of biology. The goal of the BioCreAtIvE exercise was to evaluate the performance of current text mining systems. We...
Simon B. Rice, Goran Nenadic, Benjamin J. Stapley