Background: Phylogenetic analysis can be used to divide a protein family into subfamilies in the absence of experimental information. Most phylogenetic analysis methods utilize mu...
Background: In microarray experiments the numbers of replicates are often limited due to factors such as cost, availability of sample or poor hybridization. There are currently fe...
In the paper we address the Distance-Constrained Capacitated Vehicle Routing Problem (DCVRP), where k minimum-cost routes through a central depot have to be constructed so as to co...
Roberto De Franceschi, Matteo Fischetti, Paolo Tot...
Background: Popular methods to reconstruct molecular phylogenies are based on multiple sequence alignments, in which addition or removal of data may change the resulting tree topo...
Olivier Bastien, Philippe Ortet, Sylvaine Roy, Eri...
Background: It is a major challenge of computational biology to provide a comprehensive functional classification of all known proteins. Most existing methods seek recurrent patte...