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» The Model Evolution Calculus
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BMCBI
2010
125views more  BMCBI 2010»
13 years 9 months ago
Haplotype allelic classes for detecting ongoing positive selection
Background: Natural selection eliminates detrimental and favors advantageous phenotypes. This process leaves characteristic signatures in underlying genomic segments that can be r...
Julie Hussin, Philippe Nadeau, Jean-Françoi...
BMCBI
2010
178views more  BMCBI 2010»
13 years 9 months ago
Applications of a formal approach to decipher discrete genetic networks
Background: A growing demand for tools to assist the building and analysis of biological networks exists in systems biology. We argue that the use of a formal approach is relevant...
Fabien Corblin, Eric Fanchon, Laurent Trilling
BMCBI
2010
135views more  BMCBI 2010»
13 years 9 months ago
A classification approach for genotyping viral sequences based on multidimensional scaling and linear discriminant analysis
Background: Accurate classification into genotypes is critical in understanding evolution of divergent viruses. Here we report a new approach, MuLDAS, which classifies a query seq...
Ji Woong Kim, Yongju Ahn, Kichan Lee, Sung-Hee Par...
BMCBI
2006
87views more  BMCBI 2006»
13 years 9 months ago
Phylogeny based discovery of regulatory elements
Background: Algorithms that locate evolutionarily conserved sequences have become powerful tools for finding functional DNA elements, including transcription factor binding sites;...
Jason Gertz, Justin C. Fay, Barak A. Cohen
CORR
2006
Springer
141views Education» more  CORR 2006»
13 years 9 months ago
Ideas by Statistical Mechanics (ISM)
Ideas by Statistical Mechanics (ISM) is a generic program to model evolution and propagation of ideas/patterns throughout populations subjected to endogenous and exogenous interac...
Lester Ingber