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ALMOB
2008
85views more  ALMOB 2008»
13 years 8 months ago
Noisy: Identification of problematic columns in multiple sequence alignments
Motivation: Sequence-based methods for phylogenetic reconstruction from (nucleic acid) sequence data are notoriously plagued by two effects: homoplasies and alignment errors. Larg...
Andreas W. M. Dress, Christoph Flamm, Guido Fritzs...
ALMOB
2008
124views more  ALMOB 2008»
13 years 8 months ago
A scoring matrix approach to detecting miRNA target sites
Background: Experimental identification of microRNA (miRNA) targets is a difficult and time consuming process. As a consequence several computational prediction methods have been ...
Simon Moxon, Vincent Moulton, Jan T. Kim
ALIFE
2007
13 years 8 months ago
Synchronization Phenomena in Surface-Reaction Models of Protocells
A class of generic models of protocells is introduced, which are inspired by the “Los Alamos bug” is but which, due to their abstraction level, can be applied to a wider set o...
Roberto Serra, Timoteo Carletti, Irene Poli
ALMOB
2007
155views more  ALMOB 2007»
13 years 8 months ago
Finding coevolving amino acid residues using row and column weighting of mutual information and multi-dimensional amino acid rep
Background: Some amino acid residues functionally interact with each other. This interaction will result in an evolutionary co-variation between these residues – coevolution. Ou...
Rodrigo Gouveia-Oliveira, Anders Gorm Pedersen
BIODATAMINING
2008
96views more  BIODATAMINING 2008»
13 years 8 months ago
Fast approximate hierarchical clustering using similarity heuristics
Background: Agglomerative hierarchical clustering (AHC) is a common unsupervised data analysis technique used in several biological applications. Standard AHC methods require that...
Meelis Kull, Jaak Vilo
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