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ALIFE
2006
13 years 11 months ago
The Origin of the Eukaryotic Cell Based on Conservation of Existing Interfaces
Current theories about the origin of the eukaryotic cell all assume that during evolution a prokaryotic cell acquired a nucleus. Here, it is shown that a scenario in which the nucl...
Albert D. G. de Roos
BMCBI
2004
174views more  BMCBI 2004»
13 years 11 months ago
Implications for domain fusion protein-protein interactions based on structural information
Background: Several in silico methods exist that were developed to predict protein interactions from the copious amount of genomic and proteomic data. One of these methods is Doma...
Jer-Ming Chia, Prasanna R. Kolatkar
CSB
2005
IEEE
133views Bioinformatics» more  CSB 2005»
14 years 4 months ago
Creating a Protein Ontology Resource
Protein Data Integration approaches at the moment considers data sources as data repositories, but not as applications; which in turn may embody complex interactions with other da...
Amandeep S. Sidhu, Tharam S. Dillon, Elizabeth Cha...
BMCBI
2011
13 years 6 months ago
OrthoInspector: comprehensive orthology analysis and visual exploration
Background: The accurate determination of orthology and inparalogy relationships is essential for comparative sequence analysis, functional gene annotation and evolutionary studie...
Benjamin Linard, Julie D. Thompson, Olivier Poch, ...
NAR
2007
121views more  NAR 2007»
13 years 10 months ago
WormBase: new content and better access
WormBase (http://wormbase.org), a model organism database for Caenorhabditis elegans and other related nematodes, continues to evolve and expand. Over the past year WormBase has a...
Tamberlyn Bieri, Darin Blasiar, Philip Ozersky, Ig...