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    BMCBI
    2007
    120views more  BMCBI 2007»
    Quantitative sequence-function relationships in proteins based on gene ontology
    13 years 9 months ago
    Quantitative sequence-function relationships in proteins based on gene ontology
    Download  www.biomedcentral.com
    Background: The relationship between divergence of amino-acid sequence and divergence of function among homologous proteins is complex. The assumption that homologs share function...
    Vineet Sangar, Daniel J. Blankenberg, Naomi Altman...
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    CIBCB
    2009
    IEEE
    172views Computational Biology» more  CIBCB 2009»
    Improved prediction of trans-membrane spans in proteins using an artificial neural network
    13 years 10 months ago
    Improved prediction of trans-membrane spans in proteins using an artificial neural network
    Download  www.meilerlab.org
    Tools for the identification of trans-membrane spans from the protein sequence are widely used in the experimental community. Computational structural biology seeks to increase the...
    Julia Koehler, Ralf Mueller, Jens Meiler
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    ICML
    2008
    IEEE
    90views Machine Learning» more  ICML 2008»
    Sequence kernels for predicting protein essentiality
    14 years 10 months ago
    Sequence kernels for predicting protein essentiality
    Download  cs.nyu.edu
    The problem of identifying the minimal gene set required to sustain life is of crucial importance in understanding cellular mechanisms and designing therapeutic drugs. This work d...
    Cyril Allauzen, Mehryar Mohri, Ameet Talwalkar
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    RECOMB
    2003
    Springer
    123views Computational Biology» more  RECOMB 2003»
    A multi-expert system for the automatic detection of protein domains from sequence information
    14 years 10 months ago
    A multi-expert system for the automatic detection of protein domains from sequence information
    Download  www.cbcb.umd.edu
    We describe a novel method for detecting the domain structure of a protein from sequence information alone. The method is based on analyzing multiple sequence alignments that are ...
    Niranjan Nagarajan, Golan Yona
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    BMCBI
    2006
    147views more  BMCBI 2006»
    QPath: a method for querying pathways in a protein-protein interaction network
    13 years 9 months ago
    QPath: a method for querying pathways in a protein-protein interaction network
    Download  www.biomedcentral.com
    Background: Sequence comparison is one of the most prominent tools in biological research, and is instrumental in studying gene function and evolution. The rapid development of hi...
    Tomer Shlomi, Daniel Segal, Eytan Ruppin, Roded Sh...
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