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BMCBI
2005
118views more  BMCBI 2005»
13 years 7 months ago
Variation in structural location and amino acid conservation of functional sites in protein domain families
Background: The functional sites of a protein present important information for determining its cellular function and are fundamental in drug design. Accordingly, accurate methods...
Birgit Pils, Richard R. Copley, Jörg Schultz
BMCBI
2006
120views more  BMCBI 2006»
13 years 7 months ago
Integrating protein structures and precomputed genealogies in the Magnum database: Examples with cellular retinoid binding prote
Background: When accurate models for the divergent evolution of protein sequences are integrated with complementary biological information, such as folded protein structures, anal...
Michael E. Bradley, Steven A. Benner
NAR
2008
119views more  NAR 2008»
13 years 7 months ago
MALISAM: a database of structurally analogous motifs in proteins
MALISAM (manual alignments for structurally analogous motifs) represents the first database containing pairs of structural analogs and their alignments. To find reliable analogs, ...
Hua Cheng, Bong-Hyun Kim, Nick V. Grishin
NAR
2000
120views more  NAR 2000»
13 years 7 months ago
SCOP: a Structural Classification of Proteins database
The Structural Classification of Proteins (SCOP) database provides a detailed and comprehensive description of the relationships of all known proteins structures. The classificati...
Loredana Lo Conte, Bart Ailey, Tim J. P. Hubbard, ...
NAR
2002
138views more  NAR 2002»
13 years 7 months ago
The Protein Information Resource: an integrated public resource of functional annotation of proteins
The Protein Information Resource (PIR) serves as an integrated public resource of functional annotation of protein data to support genomic/proteomic research and scientific discov...
Cathy H. Wu, Hongzhan Huang, Leslie Arminski, Jorg...